Protocol for the economic evaluation of a complex intervention to improve the mental health of maltreated infants and children in foster care in the UK (The BeST? services trial)

Introduction: Children who have experienced abuse and neglect are at increased risk of mental and physical health problems throughout life. This places an enormous burden on individuals, families and society in terms of health services, education, social care and judiciary sectors. Evidence suggests that early intervention can mitigate the negative consequences of child maltreatment, exerting long-term positive effects on the health of maltreated children entering foster care. However, evidence on cost-effectiveness of such complex interventions is limited. This protocol describes the first economic evaluation of its kind in the UK. Methods and analysis: An economic evaluation alongside the Best Services Trial (BeST?) has been prospectively designed to identify, measure and value key resource and outcome impacts arising from the New Orleans intervention model (NIM) (an infant mental health service) compared with case management (CM) (enhanced social work services as usual). A within-trial economic evaluation and long-term model from a National Health Service/Personal Social Service and a broader societal perspective will be undertaken alongside the National Institute for Health Research (NIHR)–Public Health Research Unit (PHRU)-funded randomised multicentre BeST?. BeST? aims to evaluate NIM compared with CM for maltreated children entering foster care in a UK context. Collection of Paediatric Quality of Life Inventory (PedsQL) and the recent mapping of PedsQL to EuroQol-5-Dimensions (EQ-5D) will facilitate the estimation of quality-adjusted life years specific to the infant population for a cost–utility analysis. Other effectiveness outcomes will be incorporated into a cost-effectiveness analysis (CEA) and cost-consequences analysis (CCA). A long-term economic model and multiple economic evaluation frameworks will provide decision-makers with a comprehensive, multiperspective guide regarding cost-effectiveness of NIM. The long-term population health economic model will be developed to synthesise trial data with routine linked data and key government sector parameters informed by literature. Methods guidance for population health economic evaluation will be adopted (lifetime horizon, 1.5% discount rate for costs and benefits, CCA framework, multisector perspective). Ethics and dissemination: Ethics approval was obtained by the West of Scotland Ethics Committee. Results of the main trial and economic evaluation will be submitted for publication in a peer-reviewed journal as well as published in the peer-reviewed NIHR journals library (Public Health Research Programme). Trial registration number: NCT02653716; Pre-results

The Madwoman and the Blindman: Jane Eyre, Discourse, Disability

The corpus of the madwoman : toward a feminist disability studies theory of embodiment and mental illness / Elizabeth J. Donaldson -- The blindman in the classic : feminisms, ocularcentrism, and Jane Eyre / David Bolt -- "On the spectrum" : rereading contact and affect in Jane Eyre / Julia Miele Rodas -- From India-rubber back to flesh : a reevaluation of male embodiment in Jane Eyre / Margaret Rose Torrell -- From custodial care to caring labor : the discourse of who cares in Jane Eyre / D. Christopher Gabbard -- "I began to see" : Biblical models of disability in Jane Eyre / Essaka Joshua -- Illness, disability, and recognition in Jane Eyre / Susannah Mintz -- Visions of Rochester : screening desire and disability in Jane Eyre / Martha Stoddard Holmes.Item embargoed for five year

1/2, 1/4 and 1/8 BPS Equations in SUSY Yang-Mills-Higgs Systems -- Field Theoretical Brane Configurations --

We systematically classify 1/2, 1/4 and 1/8 BPS equations in SUSY gauge theories in d=6, 5, 4, 3 and 2 with eight supercharges, with gauge groups and matter contents being arbitrary. Instantons (strings) and vortices (3-branes) are only allowed 1/2 BPS solitons in d=6 with N=1 SUSY. We find two 1/4 BPS equations and the unique 1/8 BPS equation in d=6 by considering configurations made of these field theory branes. All known BPS equations are rederived while several new 1/4 and 1/8 BPS equations are found in dimension less than six by dimensional reductions.Comment: 41 pages, no figures, v2: 49 pages, no figures, typos corrected, references added, the final version in NP